Klofanmaks

About this product

KLOFANMAX

INSTRUCTIONS FOR USE OF THE MEDICINAL PRODUCT

Trade name: KLOFANMAX

Dosage form: vaginal and rectal suppositories

Composition

Each suppository contains:

·        Active ingredients: extract of chamomile flowers — 0.05; calendula extract — 0.05; thick extract of walnut — 0.1; sea buckthorn oil — 0.01.

Suppository base: hard fat (Witepsol, H15/W35 grade; Supposir, NA15/NAS50 grade, or hydrogenated fat (culinary, frying) — 60 parts; paraffin — 20 parts; cocoa butter — 30 parts).

Description

Suppositories ranging from white to dark orange in color, torpedo-shaped.

Pharmacotherapeutic group

A medicinal product primarily used in gynecology.

Pharmacological properties

Chamomile (Chamomilla recutita L., syn. Matricaria chamomilla L.) contains 0.2–0.8% essential oil, including chamazulene. It also contains terpenes, sesquiterpenes, cadinene, farnesene, the sesquiterpene alcohol bisabolol, caprylic acid, and isovaleric acid. It has anti-inflammatory, hemostatic, antiseptic, mildly astringent, analgesic, sedative, anticonvulsant, diaphoretic, and choleretic effects. Chamomile essential oil has disinfectant and diaphoretic effects, relieves pain, reduces inflammatory processes, and normalizes impaired gastrointestinal function. Chamomile preparations accelerate epithelial regeneration in experimental ulcers and delay the development of inflammation.

Calendula flower extract (Calendula officinalis flower extract) combines numerous beneficial properties. It contains carotenoids — pigments necessary for vitamin A production; sterols — alcohols structurally similar to cholesterol, which may be absorbed instead of cholesterol and contribute to lowering its level. Calendula flower extract is a source of significant amounts of triterpenoids, including glycosides of oleanolic acid, which have a pronounced anti-inflammatory effect. Flavonoids help relieve smooth-muscle spasms; essential oils and coumarins are also present. Calendula acts as an emollient and has soothing and anti-inflammatory effects. It is used therapeutically as an antiseptic, anti-inflammatory, and wound-healing agent.

Walnut (Juglans regia, family Juglandaceae) is a valuable medicinal plant containing proteins, fats, and biologically active substances. It contains organic and phenolcarboxylic acids, flavonoids, a large amount of ascorbic acid (up to 2%), vitamins, carotenoids, quinones, tannins, and minerals. Flavonoids have antitumor activity as well as antiviral and antimicrobial effects, which are relevant to the treatment of hemorrhoids, proctitis, and other proctological diseases.

Sea buckthorn oil (Oleum Hippopheae) stimulates reparative processes in the skin and mucous membranes, accelerates healing of damaged tissues, and has an anti-inflammatory effect. It has antioxidant and cytoprotective effects; due to fat-soluble bioantioxidants, it reduces the intensity of free-radical processes and protects cellular and subcellular membranes from damage.

Indications for use

KLOFANMAX suppositories are recommended for the treatment of certain female diseases: inflammatory and non-infectious diseases of the vagina and perineum; sexually transmitted infectious diseases, including bacterial vaginosis, candidiasis, and trichomoniasis. During menopause, they are effective for atrophic colpitis and vaginal dryness. They are used as part of complex therapy for endometritis, endocervicitis, and salpingo-oophoritis. KLOFANMAX accelerates tissue recovery after cauterization of the cervix for erosion. It is also effective in inflammatory diseases of the urinary tract, such as urethritis and cystitis. KLOFANMAX helps restore the natural vaginal mucosa.

Method of administration and dosage

Vaginal use: 1 suppository 1–2 times daily after hygienic procedures.

Rectal use: 1 suppository 1–2 times daily after spontaneous bowel evacuation or an enema. After removing the suppository from the blister cell, insert it deeply into the rectum. After administration, the patient is advised to remain in bed for 30–40 minutes.

The duration of treatment with KLOFANMAX is 10–14 days. If necessary, the course may be repeated after 4–6 weeks.

Adverse effects

Allergic reactions.

Contraindications

Hypersensitivity to the components of the medicinal product and age under 18 years.

Drug interactions

No data available.

Special instructions

No habituation to the medicinal product or withdrawal syndrome has been observed.

Overdose

No cases of overdose have been described.

Presentation

Vaginal and rectal suppositories: 5 suppositories in a blister-cell package made of polyvinyl chloride film or polyethylene-laminated polyvinyl chloride film. Two blister-cell packages together with the instructions for use are placed in a cardboard box.

Storage conditions

Store out of the reach of children and protected from light at a temperature not exceeding 25°C.

Shelf life

2 years. Do not use after the expiry date.

Pharmacy dispensing

Available without a prescription.

Manufacturer

ALIANCE FARM LLC, Republic of Uzbekistan.

Seller